[HTML][HTML] T-cell factors as transcriptional inhibitors: activities and regulations in vertebrate head development
J Bou-Rouphael, BC Durand - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
… describes the activities and regulatory modes of TCF/LEF as transcriptional repressors, with
… of TCF7L1 repressor activities in both SO formation, and forebrain progenitor proliferation. …
… of TCF7L1 repressor activities in both SO formation, and forebrain progenitor proliferation. …
[HTML][HTML] Rspo2 inhibits TCF3 phosphorylation to antagonize Wnt signaling during vertebrate anteroposterior axis specification
AH Reis, SY Sokol - Scientific reports, 2021 - nature.com
… formation 38,39 , suggesting that they could be responsible for the observed Rspo2 activity.
… is predicted to be rescued by a constitutive TCF3 repressor that does not bind β-catenin (∆…
… is predicted to be rescued by a constitutive TCF3 repressor that does not bind β-catenin (∆…
Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation
RM Young, KB Ewan, VP Ferrer, ML Allende… - Elife, 2019 - elifesciences.org
… To assess if tcf7l2 repressor activity can functionally compensate for loss of tcf7l1a, we …
Repressor activity of headless/Tcf3 is essential for vertebrate head formation. Nature 407:…
Repressor activity of headless/Tcf3 is essential for vertebrate head formation. Nature 407:…
Integration of Wnt and FGF signaling in the Xenopus gastrula at TCF and Ets binding sites shows the importance of short-range repression by TCF in patterning the …
RAS Kjolby, M Truchado-Garcia, S Iruvanti… - …, 2019 - journals.biologists.com
… repressors to potential Wnt targets in the Xenopus gastrula. … The repressive activity of TCF3
is essential for its role in dorsal… , a gap in expression is formed in ring genes, whereas if we …
is essential for its role in dorsal… , a gap in expression is formed in ring genes, whereas if we …
[HTML][HTML] Nanog safeguards early embryogenesis against global activation of maternal β-catenin activity by interfering with TCF factors
… repressor of maternal β-catenin signaling to safeguard the embryo against hyperactivation of
maternal β-catenin activity … -catenin activity is crucial for proper dorsoventral axis formation. …
maternal β-catenin activity … -catenin activity is crucial for proper dorsoventral axis formation. …
[HTML][HTML] Zebrafish as an animal model for biomedical research
… signaling pathway is essential in head/brain formation and patterning in vertebrate animals.
… Whole-body metabolism is the sum of all metabolic activity of individual organs that …
… Whole-body metabolism is the sum of all metabolic activity of individual organs that …
dTcf/Pangolin suppresses growth and tumor formation in Drosophila
S Song, D Andrejeva, FCP Freitas… - Proceedings of the …, 2019 - National Acad Sciences
… animal growth and aberrant activity in this signaling cascade … Nineteen Wnt family members
are present in vertebrates. Even … -TLE/Gro repressor complex suppresses tumor formation in …
are present in vertebrates. Even … -TLE/Gro repressor complex suppresses tumor formation in …
Validation and Characterization of TCF7L1-SALL4 Protein-Protein Interaction in Mouse Embryonic Stem Cells
C Seo - 2019 - macsphere.mcmaster.ca
… formation cooperatively with BMP signaling, by forming organizing centers. A Wnt-β-catenin
signaling gradient is established in post-gastrulation vertebrate … is a dedicated repressor. In …
signaling gradient is established in post-gastrulation vertebrate … is a dedicated repressor. In …
[HTML][HTML] Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis
… into mechanisms underlying the temporal activity of Satb2. … craniofacial development and
bone formation in mammals, … Satb2 acts as a transcriptional repressor of the same group …
bone formation in mammals, … Satb2 acts as a transcriptional repressor of the same group …
Negative regulation of IL-8 in human astrocytes depends on β-catenin while positive regulation is mediated by TCFs/LEF/ATF2 interaction
KRF Robinson, SD Narasipura, J Wallace, EM Ritz… - Cytokine, 2020 - Elsevier
… factors, displacing co-repressors such as transducing-like … as either an activator or repressor
of transcription, depending … relevant to its basal and inducible activity, we performed site-…
of transcription, depending … relevant to its basal and inducible activity, we performed site-…